A to Z: Stevens-Johnson Syndromeenparentshttps://kidshealth.org/EN/images/headers/P-khAZDictionary-enHD-AR1.jpgLearn about problems of the immune system and adverse reactions to drugs or infections.Stevens-Johnson syndrome, SJS, toxic epidermal necrosis, TEN, erythema multiforme, erythema multiforme major, rashes, skin disorders, mucous membranes, Lyell's syndrome, herpes, drug reactions, infections02/11/201304/11/201909/02/20194e0a8c18-f017-44ea-b185-1dbe2b12709ahttps://kidshealth.org/ws/RadyChildrens/en/parents/az-sjs.html/<p><em>May also be called: SJS; Erythema Multiforme Major; Lyell's Syndrome; Toxic Epidermal Necrolysis.</em></p> <p>Stevens-Johnson syndrome is a rare inflammatory disorder affecting the <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/skin-hair-nails.html/">skin</a> and mucous membranes. It's usually triggered by exposure to an infection or a medication.</p> <h3>More to Know</h3> <p>In Stevens-Johnson syndrome, the <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/immune.html/">immune system</a> overreacts to a medication or infection. This causes flu-like symptoms, <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/fever.html/">fever</a>, blistering of the mucous membranes, and a red or purplish rash. In places, the top layer of skin may separate from the underlying layers, blister, and shed, leaving raw, exposed skin.</p> <p>SJS usually affects the mouth, nose, and eyes, but also can occur in&nbsp;the mucous membranes lining the ears; eyes; vagina; and urinary, respiratory, and gastrointestinal tracts.</p> <p>Medications that are most likely to be involved in Stevens-Johnson syndrome include certain antibiotics, anti-seizure medications, and pain relievers. In children, infections with herpes viruses or <em>Mycoplasma pneumoniae</em> bacteria are often triggers.</p> <h3>Keep in Mind</h3> <p>Stevens-Johnson syndrome is a serious condition that requires immediate medical attention. If the trigger of the condition can be identified and avoided, a recurrence of Stevens-Johnson syndrome is unlikely. However, some cases happen without any known trigger.</p> <p>In a similar but more severe form of the condition known as toxic epidermal necrolysis, greater areas of skin shedding occurs that can be life threatening.</p> <p><em>All A to Z dictionary entries are regularly reviewed by KidsHealth medical experts.</em></p>
Erythema MultiformeBy the looks of the "bulls-eye" marks this rash leaves on the skin, you might think it's cause for concern. But erythema multiforme clears up on its own within a few weeks.https://kidshealth.org/ws/RadyChildrens/en/parents/erythema-multiforme.html/db4a728e-f899-4989-a6cd-16b20f698866
Erythema ToxicumErythema toxicum is a common rash seen in full-term newborns. No treatment is needed and it goes away on its own.https://kidshealth.org/ws/RadyChildrens/en/parents/erythema-toxicum.html/7909189e-4070-48f4-a843-af7124c3d7f6