A to Z: Spondyloepiphyseal Dysplasia (SED)enparentshttps://kidshealth.org/EN/images/headers/P-khAZDictionary-enHD-AR1.jpgLearn about genetic disorders and conditions that affect growth and development.Spondyloepiphyseal dysplasia, SED, spondylo-epiphyseal dysplasia, spondyloepiphyseal dysplasia congenita, SED congenita, spondyloepiphyseal dysplasia tarda, SED tarda, X-linked spondyloepiphyseal dysplasia tarda, X-linked SED, vertebrae, bones, cartilage, epiphyses, spine, kyphosis, lordosis, scoliosis, type II collagen, sedlin, clubfoot, cleft palate, barrel chest, dwarfism10/11/201303/21/201909/02/20197b47e8a5-3b37-45fc-85c8-ab82b6fb86f6https://kidshealth.org/ws/RadyChildrens/en/parents/az-sed.html/<p><em>May also be called: SED</em></p> <p>Spondyloepiphyseal dysplasia (spon-dih-low-ep-ih-FIZ-ee-ul dis-PLAY-zhee-uh), or SED, is a term that refers to a rare group of skeletal conditions that cause a type of <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/dwarfism.html/">dwarfism</a> in which people have shortened trunks and limbs.</p> <h3>More to Know</h3> <p>Spondyloepiphyseal dysplasias are <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/about-genetics.html/">genetic</a> conditions that affect the development of bones in the spine (vertebrae) and the ends of long bones that are near the joints. This results in short stature with a very short trunk and limbs, although hands and feet may be more average-sized.</p> <p>People with SED usually have barrel chests, short necks, and abnormal curvature of the spine that may get worse as they age. SED also can be associated with vision and hearing problems, <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/az-clubfoot.html/">clubfeet</a>, <a class="kh_anchor">cleft palate</a>, arthritis, and difficulty with the <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/lungs.html/">respiratory system</a> as the spine curvature becomes worse.</p> <p>The two main types of SED are:</p> <ol> <li><strong>SED congenita</strong>, in which short stature is apparent at birth.</li> <li><strong>SED tarda</strong>, in which&nbsp;a lack of growth in the trunk area may not become apparent until a child is between 5 and 10 years old.</li> </ol> <p>Both types are caused by mutations in genes that are responsible for making proteins the body needs to form cartilage and bone. Most cases of SED are due to a random mutation in the genes, but the condition can be inherited from a parent.</p> <p>Treatment for SED involves treating complications like vision loss and spinal curvature as they arise.</p> <h3>Keep in Mind</h3> <p>There is no cure for SED, but it doesn't reduce life expectancy. People with SED may require regular monitoring by doctors to help prevent and treat complications.</p> <p><em>All A to Z dictionary entries are regularly reviewed by KidsHealth medical experts.</em></p>
A to Z: AchondroplasiaAchondroplasia is a genetic disorder that interferes with bone growth and causes dwarfism (short stature).https://kidshealth.org/ws/RadyChildrens/en/parents/az-achondroplasia.html/b7bb511a-fc3c-4d30-a041-4732bcb5a653
A to Z: ChondrodystrophyLearn about genetic disorders and conditions that affect growth and development.https://kidshealth.org/ws/RadyChildrens/en/parents/az-chondrodystrophy.html/5109bac1-3ef5-4c4d-bd23-5fcf00cbf956
A to Z: Diastrophic DysplasiaDiastrophic dysplasia is a rare genetic disorder that interferes with bone development and causes abnormal bone growth and dwarfism (short stature). https://kidshealth.org/ws/RadyChildrens/en/parents/az-diastrophic-dysplasia.html/1a06f093-7213-4efc-bbf6-7822c0121b8e
A to Z: Pituitary DwarfismPituitary dwarfism is a condition in which the pituitary gland does not make enough growth hormone, resulting in a child's slow growth pattern and unusually small stature.https://kidshealth.org/ws/RadyChildrens/en/parents/az-pituitary-dwarfism.html/902200ed-bb04-4c8b-a3f3-feb45256b728
All About GeneticsRead the basics about genetics, including how certain illnesses, or increased risks for certain illnesses, pass from generation to generation.https://kidshealth.org/ws/RadyChildrens/en/parents/about-genetics.html/0a35cfc5-5d12-46d2-b0a9-ffae83cace5c
Birth DefectsSome birth defects are minor and cause no problems; others cause major disabilities. Learn about the different types of birth defects, and how to help prevent them.https://kidshealth.org/ws/RadyChildrens/en/parents/birth-defects.html/eeaa74ff-3f65-4df3-8757-9df2d014c2ee
DwarfismA dwarf is a short-statured person whose adult height is 4 feet 10 inches or under. Find out what happens when a person has dwarfism and why some people are born with it.https://kidshealth.org/ws/RadyChildrens/en/teens/dwarfism.html/0d97a6fa-3509-4331-9ccd-8c6bd28ff360
Genetic TestingAdvances in genetic testing help doctors diagnose and treat certain illnesses. The type of test done depends on which condition a doctor checks for.https://kidshealth.org/ws/RadyChildrens/en/parents/genetics.html/cbe49a95-6833-41f4-881a-c26287c4a33c
Growth ProblemsIn most cases, teens who are small are just physically maturing a bit more slowly than their friends. Occasionally, though, there's a medical reason why some kids and teens stop growing. Find out about growth problems and how doctors can help.https://kidshealth.org/ws/RadyChildrens/en/teens/growth-hormone.html/439c5515-a0d3-425e-9e5d-4cc0fb91d8b4
Prenatal Genetic CounselingGenetic counselors work with people who are either planning to have a baby or are pregnant to determine whether they carry the genes for certain inherited disorders. Find out more.https://kidshealth.org/ws/RadyChildrens/en/parents/genetic-counseling.html/ce3b2896-0a32-4c87-aa11-b2a7da9d790b
When Your Baby Has a Birth DefectIf your child has a birth defect, you don't have to go it alone - many people and resources are available to help you.https://kidshealth.org/ws/RadyChildrens/en/parents/baby-has-birth-defect.html/9c0573a4-68a2-4d7d-a868-26999e332361
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