A to Z: Polyarteritis Nodosaenparentshttps://kidshealth.org/EN/images/headers/P-khAZDictionary-enHD-AR1.jpgLearn about polyarteritis nodosa (PAN), a rare disease causing inflammation of the blood vessels.Polyarteritis nodosa, PAN, periarteritis nodosa, Kussmaul's disease, vasculitis, blood vessels, arteries, Cutaneous polyarteritis nodosa, skin rashes, muscle aches, fatigue, abdominal pain, kidney problems06/12/201304/11/201909/02/201968466e0e-e854-49ee-86fe-351011837e57https://kidshealth.org/ws/RadyChildrens/en/parents/az-polyarteritis.html/<p><em>May also be called: Periarteritis Nodosa;</em> <em>Panarteritis Nodosa;</em> <em>Kussmaul's Disease</em></p> <p>Polyarteritis nodosa (PAN) is a rare disease affecting the <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/blood.html/">blood</a> vessels. Small to medium-sized arteries become inflamed (this is called vasculitis), causing damage to the arteries and the body's organs.</p> <h3>More to Know</h3> <p>Arteries carry oxygen-rich blood to tissues and organs. With PAN, <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/immune.html/">immune</a> cells attack the arteries, causing disruption in the blood supply. As a result, tissues and organs can't receive enough oxygen and nourishment to function properly.</p> <p>There is no known cause or cure for polyarteritis nodosa (pol-ee-ar-ter-EYE-tis no-DOE-suh). People with active <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/hepatitis.html/">hepatitis</a> B and C are at higher risk for developing the condition.</p> <p>Polyarteritis nodosa can involve many different areas of the body including the skin, heart, kidneys, joints, nerves, muscles, and intestines.</p> <p>Symptoms are wide-ranging and depend upon which organs are affected. They can include skin rashes and ulcers, muscle and joint aches, fever, fatigue, weakness, abdominal pain, and loss of appetite. Nerve pain and numbness also can be associated with PAN. Serious complications can include <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/strokes.html/">strokes</a>, <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/seizure.html/">seizures</a>, and kidney failure.</p> <h3>Keep in Mind</h3> <p>While polyarteritis nodosa can be serious, many people with the condition do very well. Early diagnosis and treatment with immunosuppressant drugs can put people into short- or long-term remission.</p> <p><em>All A to Z dictionary entries are regularly reviewed by KidsHealth medical experts.</em></p>
BloodHere are the basics about the life-sustaining fluid called blood.https://kidshealth.org/ws/RadyChildrens/en/parents/blood.html/79380405-c704-478c-a739-1d19c414015b
Heart and Circulatory SystemThe heart and circulatory system (also called the cardiovascular system) make up the network that delivers blood to the body's tissues.https://kidshealth.org/ws/RadyChildrens/en/teens/heart.html/fde8120a-c54e-4e57-94b8-fb4375c29487
HepatitisHepatitis is an inflammation of the liver. Most cases are caused by a virus — either hepatitis A, hepatitis B, or hepatitis C — all of which can be passed to others by someone who is infected. https://kidshealth.org/ws/RadyChildrens/en/parents/hepatitis.html/7c50e331-b71a-4410-8b0c-fc7f7fff6206
Hepatitis B Hepatitis B can move from one person to another through blood and other body fluids. For this reason, people usually get it through unprotected sex or by sharing needles.https://kidshealth.org/ws/RadyChildrens/en/teens/std-hepatitis.html/e5fcf561-94c5-464c-943e-cdb2fb1e6552
Kidneys and Urinary TractThe bean-shaped kidneys, each about the size of a child's fist, are essential to our health. Their most important role is to filter blood and produce urine.https://kidshealth.org/ws/RadyChildrens/en/parents/kidneys-urinary.html/0cbf3444-1a45-4512-9af9-bc76e5592336
Your Child's Immunizations: Hepatitis B Vaccine (HepB)Find out when and why your child needs this vaccine.https://kidshealth.org/ws/RadyChildrens/en/parents/hepb-vaccine.html/31449e00-2867-4201-8952-5fd19ae3ac05
Your Heart & Circulatory SystemYour heart is a hard-working muscle. Find out more in this article for kids.https://kidshealth.org/ws/RadyChildrens/en/kids/heart.html/9730472f-2ef1-413a-92bf-041c533b9564
kh:age-allAgesOrAgeAgnostickh:clinicalDesignation-hematologykh:clinicalDesignation-immunologykh:genre-dictionarykh:primaryClinicalDesignation-rheumatologyPhttps://kidshealth.org/ws/RadyChildrens/en/parents/dictionary/p/e492181e-6c97-4cd3-8738-cebc1f62bc38Heart Conditionshttps://kidshealth.org/ws/RadyChildrens/en/parents/hearthealth/heartconditions/ba7116cf-3c46-4896-8429-8be5c439795e