A to Z: Diabetes Insipidus, Centralenparentshttps://kidshealth.org/EN/images/headers/P-khAZDictionary-enHD-AR1.jpgIn central diabetes insipidus, the kidneys make large amounts of urine, causing the body to lose too much water.diabetes, central diabetes, kidneys, urine, pee, peeing, hormone, hormone deficiency, diuretic, ADH, thirst, dehydration, vasopressin, antidiuretic hormone, insipidus, diabetes insipidus, central diabetes insipidus, hormones, endocrine, immune system11/13/201303/25/201909/02/20199beeaeec-2438-4d73-ab88-bd2263eebfbfhttps://kidshealth.org/ws/RadyChildrens/en/parents/az-central-diabetes-insipidus.html/<p>In central <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/center/diabetes-center.html/">diabetes</a> insipidus, the body doesn't produce enough antidiuretic hormone (ADH), also called vasopressin. ADH, made by an area of the brain called the hypothalamus, helps balance the amount of water and salts in the body.</p> <h3>More to Know</h3> <p><span>Without enough ADH, the kidneys can't keep enough water in the body. As a result, </span>people with central diabetes insipidus&nbsp;lose too much water in their urine (pee). They may pee often and in large amounts, get up in the night to drink or pee, wet the bed, feel thirsty a lot, or become <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/dehydration.html/">dehydrated</a>.</p> <p><img title="illustration" src="https://kidshealth.org/ES/images/illustrations/P-diabinsipcentralA-415x233-esIL.png" alt="illustration" name="4943-DIABINSIPCENTRAL_A_ENIL.PNG" /></p> <p>The disorder often happens when the body's <a href="https://kidshealth.org/ws/RadyChildrens/en/parents/immune.html/">immune system</a> mistakenly destroys cells in the hypothalamus that produce ADH. In some cases, central diabetes insipidus runs in families. It also can develop as a result of brain surgery, head injury, tumors, or other conditions that cause damage to the hypothalamus.</p> <p>When doctors suspect the diagnosis, they confirm it with the results of blood and urine tests. An MRI of the head and other tests also might be done to look for an underlying cause.</p> <h3>Keep in Mind</h3> <p>Treatment usually involves taking medicines that replace the missing ADH to help the body produce less urine. The medication can be given as a pill, nasal spray, or injections into the skin. If the diabetes insipidus is caused by a treatable underlying disorder, the doctor will treat that also.</p> <p>In some cases, kids and teens&nbsp;with central diabetes insipidus may develop low levels of other hormones made by the hypothalamus and require additional medications for treatment.</p> <p><em>All A to Z dictionary entries are regularly reviewed by KidsHealth medical experts.</em></p>
Definition: HormonesHormones are chemical substances that act like messenger molecules in the body.https://kidshealth.org/ws/RadyChildrens/en/parents/hormones.html/8b4dc79d-4939-4083-96e3-6c3836975335
Diabetes CenterDiabetes means a problem with insulin, an important hormone in the body. Find out how children with diabetes can stay healthy and do the normal stuff kids like to do.https://kidshealth.org/ws/RadyChildrens/en/kids/center/diabetes-center.html/0767277a-98f9-4541-b2f6-f3c68f43a94c
Endocrine SystemThe endocrine system influences almost every cell, organ, and function of our bodies. It is instrumental in regulating mood, growth and development, metabolism, and sexual function, among other things.https://kidshealth.org/ws/RadyChildrens/en/teens/endocrine.html/7572f55a-2090-4b77-b6d1-74740e26934d
Immune SystemThe immune system, composed of special cells, proteins, tissues, and organs that protect against germs and microorganisms, is the body's defense against disease.https://kidshealth.org/ws/RadyChildrens/en/parents/immune.html/d5495b69-ecfe-4b16-a87f-a9f5664e71d6
Kidneys and Urinary TractThe bean-shaped kidneys, each about the size of a child's fist, are essential to our health. Their most important role is to filter blood and produce urine.https://kidshealth.org/ws/RadyChildrens/en/parents/kidneys-urinary.html/0cbf3444-1a45-4512-9af9-bc76e5592336
Word! HormonesHormones are special chemicals your body makes to help it do certain things - like grow up!https://kidshealth.org/ws/RadyChildrens/en/kids/word-hormones.html/21a086bd-8f27-409c-b9f7-be607060e2d0
Your Endocrine SystemThe endocrine system produces hormones, which are needed for proper body function and growth. Find out more in this article for kids.https://kidshealth.org/ws/RadyChildrens/en/kids/endocrine.html/e74a807b-43a3-42cf-971a-fcb15443e5e5
Your Immune SystemThe immune system keeps you healthy. How does it work? Find out in this article for kids.https://kidshealth.org/ws/RadyChildrens/en/kids/immune.html/6b9fad76-c866-450e-81d9-1e625343744f
Your KidneysYou need at least one kidney to live. Find out why in this article for kids.https://kidshealth.org/ws/RadyChildrens/en/kids/kidneys.html/e8b731bd-422b-4032-952a-5f2223257f23