Intractable epilepsy is
when seizures can't be controlled by medicines. (Intractable means "not easily managed
or relieved.") It's also called refractory, uncontrolled, or drug-resistant epileptic
About 1 in 3 of people with epilepsy have intractable
What Happens in Intractable Epilepsy?
Intractable epilepsy happens when the medicine prescribed for a seizure type doesn't
work, stops working, or causes severe side effects that make it difficult to use.
Seizures caused by tumors, scarring from brain injury,
or lack of oxygen also can be intractable.
How Is Intractable Epilepsy Diagnosed?
Intractable epilepsy usually is diagnosed after three carefully chosen, safe medicines
don't completely control the seizures. The chances of a fourth medicine working are
very low, so doctors will diagnose intractability at this point.
How Is Intractable Epilepsy Treated?
When medicines do not prevent a child's seizures, doctors may recommend a special
diet, like the high-fat, low-carbohydrate ketogenic
Sometimes they recommend vagal nerve stimulation
(VNS). In VNS, an implanted device (a stimulator) sends mild pulses of electrical
energy to the brain through the vagus nerve.
surgery might be an option for about half of children with intractable epilepsy.
Most of them can benefit significantly from surgery.
How Can I Help My Child?
Talk to your doctor to see what treatments are available for your child. Make sure
your child takes medicines as prescribed and avoids known seizure triggers, such as
lack of sleep, antihistamine use, or excessive stress.
Always tell the doctor if you think a medicine isn't
working or you don't notice any improvement. This helps the doctor give your child
the best possible care.
It's important to keep your child safe during a seizure.
So make sure that other adults and caregivers (family members, babysitters, teachers,
coaches, etc.) know what