A craniopharyngioma (kray-nee-oh-fair-in-jee-OH-muh) is a rare type of noncancerous
(benign) brain tumor that
usually forms near the base of the pituitary gland.
More to Know
When a human embryo is developing in the womb, there is a small depression called
Rathke's pouch in the roof of the mouth. As the fetus develops, Rathke's pouch becomes
one part of the pituitary gland, a small organ located near the bottom of the brain.
In rare cases, remnants of Rathke's pouch develop into benign tumors. The tumors,
called craniopharyngiomas, don't cause cancer but can cause problems in the brain
and pituitary gland.
Craniopharyngiomas can grow and press on the brain, pituitary gland, optic nerve
(the nerve the connects the eye to the brain), or fluid-filled spaces within the brain.
This can interfere with the production of hormones, affect the normal working of the
brain, and cause headaches, slow growth, delayed puberty, and vision
problems. Craniopharyngiomas are most common in children ages 5-14, but they can affect
people of any age.
Surgery to totally remove a craniopharyngioma can sometimes damage surrounding
parts of the brain and cause a permanent shortage of some hormones. Therefore, for
most patients, a neurosurgeon first removes part of the craniopharyngioma, and then
uses radiation therapy for any remaining
tumor. This approach usually results in effective treatment of the tumor and better
quality of life for the patient.
Keep in Mind
The overall survival rate for people with craniopharyngiomas is very high with
treatment. If the tumor can be removed or treated with high doses of radiation, the
chance of a permanent cure is about 80%-90%.
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