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Lipase Blood Test

Lipase Blood Test

What Is a Lipase Blood Test and Why Is It Done?

A lipase (LIE-pace) test measures the amount of lipase in the blood. Lipase is an enzyme made by the pancreas that helps the body digest fats. A high level of lipase can be a sign that the pancreas is injured, irritated, or blocked.

Doctors may order a lipase test if a child:

  • has signs of a pancreas problem, like belly pain, nausea, or vomiting
  • takes medicine that makes problems with the pancreas more likely

Top Things to Know

  • The lipase test checks the level of an enzyme called lipase in the blood.
  • Doctors may order it if your child might have a pancreas problem.
  • Kids might need to stop taking certain medicines or not eat or drink before the blood test.
  • Your doctor can explain what it means if lipase levels are too high or too low.

How Can I Help My Child Prepare for a Blood Test?

To help kids get ready for a blood test, find out if they need to fast (not eat or drink) or should stop taking medicines before the test. Explain what to expect during the test. If your child is nervous about it, work together on ways to stay calm. Deep breathing or even imagining being in a place that makes your child feel safe and relaxed can help.

What Do Lipase Test Results Mean?

Your doctor will explain what the results of the lipase test mean for your child. What’s “normal” varies based on things like age and gender.

Increased Lipase Levels

High lipase levels might mean there’s a problem with the pancreas, kidneys, or salivary glands (which make saliva, or spit). High levels could also be a sign of celiac disease, a peptic ulcer, or that the intestines (or bowels) are blocked.

Low Lipase Levels

Low lipase levels might mean there's a long-lasting condition that could harm the pancreas, like chronic pancreatitis or cystic fibrosis.

What Else Should I Know?

If lipase levels are high or low, your child may need other tests. Some causes of high lipase get better on their own, while others need treatment. 

If you have questions about the lipase test or what the results mean, talk to your doctor.

Medically reviewed by: Larissa Hirsch, MD
Date reviewed: November 2025