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Arkansas Children's
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Little Rock, AR 72202-359
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Amylase Blood Test

Also called: Serum Amylase, “Amy” Test

Amylase Blood Test

What Is an Amylase Blood Test and Why Is It Done?

An amylase (AM-uh-lace) blood test measures the amount of an enzyme in the blood called amylase. 

Doctors may order an amylase test if a child:

  • has signs of a problem with the pancreas, like belly pain, nausea (feeling sick to the stomach), or vomiting
  • has or might have an infection, cystic fibrosis, or an eating disorder
  • takes medicine that makes problems with the pancreas more likely

What Is Amylase?

The amylase enzyme is made mostly by two digestive system organs: the salivary glands and pancreas. The enzyme is a kind of protein that helps the body digest carbohydrates, or carbs — one of the three big nutrients that make up food. 

Top Things to Know

  • The amylase blood test checks the level of an amylase (a kind of enzyme) in the blood.
  • The test can check for things like pancreas problems, infection, cystic fibrosis, and eating disorders.
  • Kids might need to stop taking certain medicines or not eat or drink before the blood test.
  • Your doctor can explain what it means if amylase levels are high or low.

How Can I Help My Child Prepare for a Blood Test?

To help kids get ready for a blood test, find out if they need to fast (not eat or drink) or should stop taking medicines before the test. Certain medicines can change the results of an amylase test. So, tell your doctor if your child is taking any medicine, especially: corticosteroids, birth control pills, opioids, or diuretics (water pills).

Explain what to expect during the test. If your child is nervous about it, work together on ways to stay calm. Deep breathing or even imagining being in a place that makes your child feel safe and relaxed can help.

What Do Amylase Test Results Mean?

Your doctor will explain what the results of the test mean for your child. “Normal” amylase levels can vary based on things like age and gender. 

High Amylase Levels

An elevated (high) level of amylase in the blood can be a sign that the pancreas is injured, irritated, or blocked. High levels could also be due to problems with the gallbladder, intestines, liver, or salivary glands. 

Low Amylase Levels

Amylase levels might be low because of a problem with the kidneys, liver, or pancreas, or things like diabetes, cystic fibrosis, or a broken bone.

What Else Should I Know?

If you have questions about the amylase test or what the results mean, talk to your doctor.

Medically reviewed by: Larissa Hirsch, MD
Date reviewed: January 2026