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Does the HPV Vaccine Cause Paralysis?

What Is the HPV Vaccine?

The HPV vaccine protects against human papillomavirus (HPV), a virus that can cause different types of cancer (such as cancer of the cervix, penis, anus, vagina, vulva, and throat) as well as genital warts. It’s a common viral infection, spread through skin-to-skin contact and sexual contact, and there is no cure.

The HPV vaccine is safe and effective. While a few people have reported short-term paralysis from a condition called Guillain-Barré syndrome (GBS) after having the HPV vaccine, experts have not found a connection between the two.

What Is Guillain-Barré Syndrome (GBS)?

GBS is a rare medical condition where the immune system attacks the nerves. People who get GBS can sometimes become paralyzed. Most of the time it's temporary, and the person gets better.

Does the HPV Vaccine Cause Guillain-Barré Syndrome (GBS)?

Scientists don't know exactly what causes GBS, but it can be brought on by infections and occasionally by vaccines. A few people have reported GBS after getting the HPV vaccine. Experts have investigated this issue closely, and have not found a connection between GBS and the HPV vaccine. They think that these people probably already had GBS but happened to get the vaccine around the same time.

Is the HPV Vaccine Safe?

The FDA has studied the HPV vaccine extensively and approved it as safe. Some people worry about the safety of the HPV vaccine since it is newer than many other routine vaccines. But it has been available since 2006, and has been found to be safe and effective.

Experts continue to monitor the vaccine to make sure it's not causing serious health problems — as they do with all vaccines.

Although all vaccines carry a small risk of an allergic reaction, any side effects with the HPV shot are mostly minor. Someone might notice swelling or pain at the site of the shot, or feel faint after getting the shot.

Other Common Questions

Who Should Get the HPV Vaccine?

Doctors recommend the vaccine for girls and boys 9–12 years old and for older kids who aren't yet vaccinated.

Teens or young adults who didn't start or complete the series of shots can get it up to age 45. (It is recommended up to age 26. After that, a person can decide with their doctor if it’s a good idea for them.)

What Can I Expect After Getting the HPV Vaccine?

Most people feel completely fine after getting the HPV vaccine. Some have minor side effects like swelling, pain, or redness of the area.

Occasionally people feel faint after getting the vaccine. By sitting down after the shot, you can make this less likely to happen. Let the doctor know about any more serious symptoms, like those of an allergic reaction.

Medically reviewed by: Larissa Hirsch, MD
Date reviewed: January 2026