Cisapride (removed from market - there may be special cases where you can still get cisapride)

(SIS a pride)

What key warnings do I need to know about before giving this drug to my child?

• An unsafe fast heartbeat may happen. Tell the doctor if your child has a history of fast heartbeats, kidney failure, low potassium or magnesium levels, or lung failure. Check all drugs with your child's doctor.
• Sometimes drugs are not safe when your child takes them with other drugs. They can cause bad side effects. This is one of those drugs. Be sure to talk to your child’s doctor about all the drugs your child takes.

Is it safe for my child to take this drug?

• Not if your child has an allergy to cisapride or any other part of this drug.
• Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
• Not if your child has any of these health problems: Fast or slow heartbeat, GI (gastrointestinal) bleeding, heart disease, hole in the GI tract, bowel block, kidney disease, low magnesium levels, low potassium levels, lung failure, or weak heart.

Why does my child need this drug?

• It is used in patients getting tube feedings who have high residuals.
• It is used to treat hard stools (constipation).
• It is used to treat heartburn.
• It is used to treat poor stomach clearing.

How does this drug work?

• Cisapride helps the stomach get rid of food and move the food out the GI (gastrointestinal) tract.

How is this drug given?

• Give 15 to 30 minutes before meals and at bedtime.
• There is a liquid (suspension) if your child cannot swallow pills. Shake well before use.
• Children who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.
• Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.

How long does this drug take to work?

• Your child may start feeling better soon after starting this drug.

What do I do if my child misses a dose? (does not apply to patients in the hospital)

• Give a missed dose as soon as you think about it.
• If it has been more than 1 hour, skip the missed dose and go back to your child's normal time.
• Do not give 2 doses or extra doses.
• Do not change the dose or stop your child's drug. Talk with your child's doctor.

What safety measures do I need to take when my child is using this drug?

• Keep a list of all your child's drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child's doctor.
• Check all drugs your child is taking with your child's doctor. This drug may not mix well with some other drugs.
• Avoid giving your child other drugs and natural products that may slow your child's actions.
• Avoid giving your child grapefruit and grapefruit juice.
• If your child has a weak heart, talk with the doctor.

What are some side effects of this drug?

• Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Have your child avoid tasks or actions that call for him/her to be alert or have clear eyesight until you see how this drug works.
• Headache.
• Belly pain or heartburn.
• Loose stools (diarrhea).

What do I need to watch for when my child is using this drug?

• Change in the health problem being treated. Is it better, worse, or about the same?
• For unwanted side effects of this drug.
• Follow up with the doctor.

When do I need to call my child's doctor?

• If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
• If you think there was an overdose, call your local poison control center or ER right away.
• If your child shows signs of a very bad reaction, call your child's doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
• If your child has a fast heartbeat.
• If your child shows signs of very bad dizziness or passes out.
• If your child has very loose stools (diarrhea).
• If your child gets a rash.
• If your child’s health problem does not get better or if you believe your child’s health problem is worse.

How do I store and/or throw out this drug?

• Store at room temperature.
• Protect from light.
• Protect tablets from water. Do not store in a bathroom or kitchen.

General drug facts

• If your child has a very bad allergy, he/she needs to wear an allergy ID at all times.
• You may get this drug by drug order only. If there are refills, call your pharmacy. If your child does not have refills left, you may need to call your child's doctor.
• Get rid of this drug when your child no longer needs it or if the drug is outdated.
• Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
• Do not share your child's drug with others and do not give anyone else's drug to your child.
• Keep all drugs out of the reach of children and pets.
• Keep a list of all your child's drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child's doctor.
• Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
• Talk with the doctor before giving your child any new drug, including OTC, natural products, or vitamins.
• If you do not use a drug the right way, it may not be safe. Follow what your child’s doctor tells you.

Copyright © 1978- Lexi-Comp Inc., The Children's Hospital, Denver, CO., and Pediatric Pharmacy Advocacy Group, Inc. All Rights Reserved. This information is protected under US and international copyright law. Unauthorized use or reproduction is prohibited.