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Can a Person Get Mono Again?

I had mono when I was 16. I'm now 25. Is it possible for me to get mono again?
- Theon

While it is possible, someone who has been infected with mononucleosis (which is caused by the Epstein-Barr virus) usually won't get the symptoms of mono again from this virus.

However, the symptoms of mono — which include tiredness, fever, sore throat, and loss of appetite — are common to many other medical conditions. So chances are, if you've been diagnosed with mono before and are now experiencing some of these symptoms, you have another infection or other medical condition. To be sure, see your doctor for an accurate diagnosis.

Reviewed by: Elana Pearl Ben-Joseph, MD
Date reviewed: February 2013